80 yr old female with k/c/o type2 DM since 15yrs came with H/o fever associated with chills since 20days,h/o dry cough since 15 days,H/o involuntary dribbling of urine while coughing since 15days,H/o generalised weakness since 4days

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Chief complaints:-

80 yr old female with k/c/o type2 DM on OHA and HTN since 15yrs came with 

C/o  fever associated with chills since 20days,

C/o dry cough since 15 days

C/o involuntary dribbling of urine while coughing since 15days, 

C/o  generalised weakness since 4days, 

Pt was found in unresponsive state,  unable to getup, difficulty in speaking, associated with sweating around 8am.Iv fluids were given

By Afternoon, pt was able to speak. 

Around 6pm, pt was again found unresponsive  associated with sweating , this episode lasted fr 2hrs. RMP was called upon . On checking vitals , BP was found to be 170/70mmhg, and was given antihypertensives , no frothing, no seizures, 

She regained consciousness for a while (5min) and again lost consciousness associated with snoring and sweating.

Pt was brought to casuality,

GRBS - 48MG/DL

After 25%D  was given, pt became conscious , she could sit and became normal. Her GRBS raised to 231mg/dl after 30min, 2.IV fluids were given,

Pt didn't take food and fluids since 2 days

No H/o headinjury, nausea, Vomitings, blurring of vision, no h/o headache, no h/o involuntary movements, No h/o decreased sensation,

HOPI:-

pt was apparently asymptomatic 20days ago later she had fever associated with chills since 20days which was gradually progressive,

h/o dry cough since 15 days no diurnal variation, no wheeze,,H/o involuntary dribbling of urine while coughing since 15days pale yellow colour,nonfoul smelling 

H/o  generalised weakness since 4days,

She had decreased food and fluid intake since 10days

Past history:-

NO H/O SIMILAR COMPLAINTS IN THE PAST

H/O DM SINCE 15YRS -

on tab glibenclamide 5mg + t. metformin 500mg

T.,pioglitazone 20mg

H/0 HTN SINCE 15 YRS on tab telma-H (40/12.5mg)

no TB/ASTHMA/EPILEPSY/CAD

-1st may 2020 when she went to hospital with complaint of burning sensation in epigastrium


Hemogram

 Rbs

Usg abdomen 
took x ray for knee pain and burning sensation in epigastrium on 5th May


She went to hospital on 15th May 2020 


She went to hospital on 15th sep 2020 with c/o anorexia,  dyspepsia and decreased sleep and was medicated with below


Her CBP ON 1/9/2020


17th nov 2020 with complain of epigastric region burning sensation 

7th feb 2021

She went to hospital with c/o of sensation of mass in throat 

14th feb 2021


Past SURGICAL HISTORY

She was hysterctomised 40yrs back for AUB

Personal history

Diet: mixed
Sleep: inadequate sleep since 20days
Bladder movements: involuntary dribbling of urine while coughing since 10 days
Bowel: regular
Addictions: chronic alocoholic (from 20yrs of age and stopped 15yrs ago after diagnosed with DM and HTN)
Appetite:decreased since 20days


Family history

No similar history in the family

Drug history

Not allergic to any known drug


General Examination:

Pt.  is conscious, coherent and cooperative

Moderately built and moderately nourished.
Pallor ,
No signs of  icterus, Cyanosis,clubbing,koilonychia,generalised lymphadenopathy, pedal edema
SIGNS OF DEHYDRATION PRESENT:DRY TONGUE 

Vitals:
on 23/3 9:50pm
O/e:- dry tongue
Temp- 98.4F
BP - 160/1O0 mmhg,right arm,supine position
PR- 88bpm,regular rate& rhythm,normal in volume
RR- 2Ocpm
SpO2 - 96% at RA

24/3/21 8:00am
O/e:- dry tongue, 
Temp- 98.4F
BP - 130/90 mmhg,right arm,supine position
PR- 96bpm,regular rate& rhythm,normal in volume

Systemic Examination:

cvs:- S1 S2 HEARD

Rs:b/l inspiratory fine crepts (left more than right)ISA,IAA, egophony+
Inspection:
Chest shape - normal
Bilaterally symmetrical movements with respiration
Trachea- central
NO wheeze
Breath sounds-vesicular
Adventitious sounds- crepts

Per abdomen 

Inspection: 
Shape- obese,distended
Umbilicus- central
All quadrants are moving equally with respiration
No scars,sinuses,engorged veins
Hernial orifices- free
Palpation:
No local rise of Temperature
Liver and spleen- not palpable
No palpable masses
Auscultation: bowel sounds are heard
CNS:

Patient is conscious, coherent, cooperative; 

well oriented to time, place and person. 

Hypoactive and drowsy on the day of admission

Speech - normal BUT there is difficulty in speaking on day of admission 

Higher mental functions- normal

cranial nerves- intact 

motor system- normal

sensory system - normal

INVESTIGATION:

CBP:

RFT:

Reticulocyte count:-

serum sodium:-24/3


CXR PA VIEW:

ECG:

Rbs: 143mg/dl 

24/3

1:00am 121mg/dl

2:00am:153mg/dl

8:00am 212mg/dl

10:00am  218mg/dl

12:00pm  200mg/dl

2:00pm 246mg/dl

25/3/21

8pm 139mg/dl

10pm 228mg/dl

12am 216mg/dl

2am 172mg/dl

4am 171mg/dl

6am 167mg/dl

8am 167mg/dl

26/3/21

8pm 182mg/dl

10pm 192mg/dl

12am 196mg/dl

2am 186mg/dl

4 am 198mg/dl

6 am 203mg/dl

Usg on 25/3/21


Serum sodium


Esr:-


Diagnosis:-

Recurrent Hypoglycemia-drug induced oha

Fever under evaluation -left lower lobe consolidation 

Anemia? IdA

Hypovolemic hyponatremia 

k/c/o DM, HTN SINCE 15YRS

TREATMENT:-

PLENTY OF ORAL FLUIDS 

1. IVF- 2 . NS @25ML/HR

2. GRBS CHARTING 4TH HRLY

3.BP CHARTING 4TH HRLY

4.TEMP CHARTING  4TH HRLY

5.SYR BENADRYL  10ML/PO/BD(1-X-1)

6.TAB PANTOP 49MG/PO/OD/BBF-8AM

Discussion:-

-Sir his motor weakness is suggestive of predominantly C7 ,C8 nerve involvement along with C6 and T1 also

But no objective sensory involvement.

So most likely is it that the medial cord of the brachial plexus got involved ? 

And how to explain his wasting sir of the proximal muscles of left upper limb?

-Wasting with increased tone in left (as mentioned in Sruthi's findings above? 

-Yes sir 

?Increased tone can be explained with 6 months back CVA and wasting with the long term peripheral neuropathy??

-

If a person with long term peripheral neuropathy develops an upper motor neuron lesion would the previous flaccid tone increase?



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